is a disease that is caused by a microorganism. The infectious disease is produced by Bartonella bacilliformis. This disease can sometimes present without symptoms, and can also present with symptoms. The clinical symptoms of the disease are pleomorphic. The signs and symptoms of Carrion’s disease can be divided into two types. This includes the acute phase and the chronic phase. Some of the general symptoms of Carrion’s disease include hepatomegaly, splenomegaly, jaundice, other types of infection, muscle aches, headaches, lymphadenopathies and so on. This disease can be diagnosed by initially taking the medical history of the patient, followed by taking the present complaints, including the signs and symptoms. The physician would proceed to carry out laboratory tests on the patient such as Giemsa stain, blood culture, immunofluorescence and so on before making and confirming the diagnosis. This disease can be treated by administering medications. One of the most effective drugs used for Carrion’s disease is chloramphenicol. Other drugs used for the treatment of this disease include rifampin or macrolides. Multiple treatments are often required for the treatment of this disease, as it often presents with comorbid infections and conditions. Stem cell therapy is also one of the ways of treating this disease. Physicians can buy stem cell online for the treatment of the disease. Stem cells can be extracted from the bone marrow of the patient, who has a high risk of an infection due to the activity of some organism. The stem cells are extracted, processed before they are intravenously given back to the patient to replace the impaired or damaged cells.
What Are The Signs And Symptoms Of Carrion’s Disease?
The signs and symptoms of Carrion’s disease are pleomorphic. However, some patients might present with no symptoms, especially people from endemic areas. The clinical presentation of Carrion’s disease can be divided into two. These are the acute phase and the chronic phase. There is a possibility for an individual to be affected by the two phases.
- Acute phase: This is also known as the hematic One of the prevalent symptoms of the acute phase is a fever. Patients usually present with a temperature of about 39 degrees. Other signs and symptoms include hepatomegaly, splenomegaly, jaundice, enlarged lymph nodes. Patients affected by the acute phase also presents with hemolytic anemia and the weakening of the immune system. Patients that are not treated, or not well managed to have a fatality ratio of about 40%. However, this could get as high as 90% when the disease occurs with opportunistic infection. Salmonella infection is one of the most common infections that occur with Carrion’s disease. Some of the other symptoms that present in the acute phase include a headache, muscle ache, and abdominal pain. A connection has been suggested between Carrion’s disease and heart murmurs. Some of the signs and symptoms presented by children include anorexia, nausea, vomiting and so on. Majority of the mortality of the disease happens in the acute phase. The common cause of death in the acute phase is mostly due to infections that occur in the patients. This happens because of immunosuppression in the affected persons. Another factor that increases the development of a weakened immune system in children is malnutrition. Pregnant women who present with the acute phase, do have a have a spontaneous abortion. The rate of abortion has been reported to be up to 40%.
- Chronic phase: This phase is also referred to as the eruptive or tissue phase. Patients do present with cutaneous rash, which is produced by a proliferation of endothelial cells. The lesions presented by affected persons by be categorized into 3 types. These are
- Miliary lesion: This kind of lesions are between 1-4 millimeters.
- Nodular lesion: This is also known as a subdermal lesion
- Mular: This is more than 5 millimeters
The above classification is based on the size of the lesions. In addition, the lesions often bleed and ulcerate. Some of the prevalent signs and symptoms of the chronic phase include fever, tiredness, malaise, myalgia, pallor, lymphadenopathy, hepatomegaly, splenomegaly and so on. Microscopically, the chronic phase and rash occur as a result of angioblastic hyperplasia. This is a process whereby there is an increased growth and volume of the cell in the tissues that form the blood vessels. This leads to a loss of contact between the cells and subsequently leads to an impairment or loss of functioning of the cells. The chronic phase is the most prevalent phase. However, the mortality rate in this phase is low, as compared to the acute phase. It is possible for an individual to present with the two phases.
What Is The Cause Of Carrion’s Disease?
Carrion’s disease is a disease that is caused by a microorganism. The infectious disease is produced by Bartonella bacilliformis
How Can This Disease Be Diagnosed?
Carrion’s disease can be diagnosed by taking a blood sample of the patient and running some laboratory tests on it. Some of the tests include Giemsa stain, blood agar culture, immunoblot, immunofluorescence and PCR
How Is Carrion’s Disease Currently Treated?
There are some cases of Carrion’s disease that requires medical or surgical procedures. However, antibiotics have been the most used and effective treatment of the disease. Chloramphenicol is one of the most commonly used medication for this disease. Carrion’s disease usually exists as a comorbid infection. It does present with other infections. Salmonella infection is one of the closely associated one. This also gives room for opportunistic diseases. This happens because of the weakened immune system of the patients. Fluoroquinolones like ciprofloxacin are usually used together with B-lactam antibiotics such as penicillin for the treatment of children affected by the disease. Either ciprofloxacin or chloramphenicol can be used by adult patients. The eruptive phase of the Carrion’s disease cannot be treated with chloramphenicol. Although other drugs such as azithromycin, erythromycin, and ciprofloxacin can also be used to treat the patients successfully. Lastly, rifampin and macrolides can also be used to treat the young and old patients.
Stem Cell Therapy And Carrion’s Disease
Stem cell therapy is also one of the ways of treating this disease. Stem cells can be extracted from the bone marrow of the patient, who has a high risk of an infection due to the activity of some organism. The stem cells are extracted, processed before they are intravenously given back to the patient to replace the impaired or damaged cells.
Frishman, W. (1998). Biologic markers as predictors of cardiovascular disease. The American Journal of Medicine, 104(6), pp.18S-27S.
Henderson, V. (1997). The epidemiology of estrogen replacement therapy and Alzheimer’s disease. Neurology, 48(Issue 5, Supplement 7), pp.27S-35S.
NAKANO, S. and YAMADA, H. (2009). Summary. Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics, 40(2), pp.27S-27S.