Impact of Genome Reduction on Bacterial Metabolism and Its Regulation | Checkbiotech

Home | Contact Us | Partnership | Site Map

left shadow

Checkbiotech - for emerging fields of science

NEWSLETTERS SUBMIT CONTENT

Checkbiotech Home

Sign In | Register

bottom shadow


	View Edit Domain: GreenBio Title: * Body: To understand basic principles of bacterial metabolism organization and regulation, but also the impact of genome size, we systematically studied one of the smallest bacteria, Mycoplasma pneumoniae. <br /> <br /> A manually curated metabolic network of 189 reactions catalyzed by 129 enzymes allowed the design of a defined, minimal medium with 19 essential nutrients. <br /> <br /> More than 1300 growth curves were recorded in the presence of various nutrient concentrations. Measurements of biomass indicators, metabolites, and 13C-glucose experiments provided information on directionality, fluxes, and energetics; integration with transcription profiling enabled the global analysis of metabolic regulation.<br /> <br /> Compared with more complex bacteria, the M. pneumoniae metabolic network has a more linear topology and contains a higher fraction of multifunctional enzymes; general features such as metabolite concentrations, cellular energetics, adaptability, and global gene expression responses are similar, however.<br /> <br /> © 2009 American Association for the Advancement of Science. All Rights Reserved.<br /> Captcha: Please Enter Code : * Time Zone: * Select the time zone Vocabularies Newsletter: Domain: Show summary in full view Input format Filtered HTML Web page addresses and e-mail addresses turn into links automatically. Lines and paragraphs break automatically. Full HTML Web page addresses and e-mail addresses turn into links automatically. Lines and paragraphs break automatically. news_filter Web page addresses and e-mail addresses turn into links automatically. More information about formatting options			Related Articles Bt corn farms expanding Insect resistance to Bt crops can be predicted, monitored an... Genome of "Orphan Crop" Pigeonpea Cracked Dow AgroSciences, BioDuro to Collaborate on Crop Protection ... Scientists Find Structure of Gene-Editing Protein Crop Improvement and Human Medicine: Using Proteins to Targe... Transgenic crops: How genes jump from crop to crop Farmers battle a super-bug Improving Crops from the Roots Up Plant genomes may help next generation respond to climate ch... Top GreenBio Articles

Home | Partnership | Contact Us | Site Map | News Site Map
© 2000-2012 Checkbiotech.org | Disclaimer