Sepsis is a life-threatening medical condition that needs urgent treatment. However, the sole reason for the huge mortality rate due to sepsis is the late detection of the disease. Studies have shown that sepsis is decreased by 7.6% per hour by the early and appropriate use of antibiotics. The early detection significantly reduces the risk and cost of treating sepsis. While detecting and diagnosing sepsis is important, a lot of physicians find it difficult successfully detecting sepsis in patients on time. This is where the Beck Coulter DxH 900 Hematology Analyzer and Early Sepsis Indicator comes in. However, before going into the details of the machine. It’s important to know some important things about sepsis.

What Is Sepsis?

Sepsis is a life-threatening complication of infections. This disease happens when their chemicals that are released into the bloodstream to fight infections, induce inflammatory reactions throughout the body. This can lead to various changes in the body, and as well cause damaging effects on the different organs of the body. Some of the common signs and symptoms of sepsis include fever, confusion, nausea, increased breathing rate, and also increase heart rate. Symptoms might also present differently, depending on the type of infection the patient has. As an illustration, respiratory infections such as pneumonia, infections of the urinary system, and so on would present differently from one another. In addition, people with a weak immune system tend to present with more serious symptoms. Severe cases of sepsis may lead to a reduction in the flow of blood to the organs. The most prevalent cause of sepsis is bacterial infections. Others include fungi, virus, parasites, and so on. There are some factors that increase the risk of developing sepsis. Some of the factors include a weakened immune system, diseases such as diabetes mellitus, burns, trauma and so on. Physicians diagnose this disease by carrying out a blood culture test on the patient. Medical imaging is also used to detect any possible infection in patients. Sepsis is a serious medical condition and has to be treated as soon as possible. Physicians treat sepsis by administering intravenous fluids, antibiotics and so on. Typically, patients affected with sepsis are treated in an intensive care unit.

What are the signs and symptoms of Sepsis?

Patients affected by sepsis present with various signs and symptoms. The manifestations presented by patients depends on the type of infection the patient has. Below are some of the general symptoms;

  • Fever
  • The patient might also present with a low body temperature.
  • Persons affected with sepsis usually do present with an increased heart rate.
  • Patients do present with a rapid breathing rate.
  • High blood sugar.
  • Reduced urination.
  • Patients when tested usually are metabolic acidotic.
  • They also present with coagulopathies.

What Are The Causes Of Sepsis?

Sepsis can occur as a result of various infections. These infections can be caused by different organisms, such as bacterial, viral, fungal and so on. Some of the most likely diseases include the following;

  • Pneumonia
  • Infection in the abdomen
  • Renal infection
  • Infection in the bloodstream

What’s Responsible For The Increasing Rate Of Sepsis?

  • Age: Studies have shown that sepsis is more prevalent in old people. The longer you live, the higher your risk of developing sepsis.
  • Drug-resistant bacteria: A lot of bacteria have become resistant to the effects of antibiotics that used to work. These antibiotic-resistant group of bacteria are responsible for the increased rate of sepsis.
  • Immune system: Sepsis tends to develop in people that have a low immune system.

What Are The Risk Factors Involved In The Development Of Sepsis?

  • Invasive hospital devices: Invasive hospital devices such as intravenous catheters, breathing tubes that are infected, can lead to the development of sepsis. This would occur more rapidly in patients that have a weak immune system.
  • Age: Studies have shown that sepsis is more prevalent in old people. The longer you live, the higher your risk of developing sepsis. In addition, people with high risks of developing sepsis include very young or very old people.
  • Patients that are already sick, and that frequent the intensive care unit, have a high chance of developing sepsis.
  • Burns: People with burns and other forms of injury have a high risk of developing sepsis.

What Are The Complications Of Sepsis?

The complications of sepsis worsen the longer the disease is left untreated. The severity of sepsis varies, from mild, to moderate and severe. Sepsis can lead to the reduction of blood flow to vital organs of the body, such as the brain, heart and the kidneys. Sepsis can also lead to the rapid formation of clots in the blood. This formed clot can travel to different parts of the body and might lodge itself in organs such as arms, legs, fingers and so on.

What Does the Beckman Coulter Dxh 900 Hematology Analyzer and Early Sepsis Indicator Do?

The Dxh 900 Hematology Analyzer and Early Sepsis Indicator is a medical gadget that enables the high-volume laboratory to achieve red blood cells, platelet, and white blood cell differentials. The machine does this through a native-state cellular characterization.

What Are The Features Of The Coulter Dxh 900 Hematology Analyzer And Early Sepsis Indicator?

  1. Produces an excellent Red blood cell, platelet, and white blood cell differential through native-state cellular characterization
  • The machine delivers reliable and reportable white blood cell differential results in one run. The technology the machine runs on provide high-resolution characterization, without changing the cell morphology, and providing an excellent blood test result.
  • Evaluates anaemia with a high accuracy by maintaining near native-state cellular characterization throughout the red blood cell maturation cycle.
  • It enhances slide interpretations through intelligent slide-making,
  • It supports critical clinical decisions through advanced platelet analysis.
  1. Ensure predictable costs and faster break-even point
  2. Increases productivity by maximizing staff time, while also providing excellent results per square meter, lesser slides, and minimal manual interventions.
  • Increases efficiency with the one-touch sample processing with total laboratory automation and clinical information management tools
  • Streamline QA/QC processes through an automated technology that can be customized, with daily reminders, and remote support.

References

HEDLEY, B., KEENEY, M., CHIN-YEE, I., & BROWN, W. (2010). Initial performance evaluation of the UniCel® DxH 800 Coulter® cellular analysis system. International Journal Of Laboratory Hematology, 33(1), 45-56. doi: 10.1111/j.1751-553x.2010.01239.x

JEAN, A., BOUTET, C., LENORMAND, B., CALLAT, M., BUCHONNET, G., & BARBAY, V. et al. (2010). The new haematology analyzer DxH 800: an evaluation of the analytical performances and leucocyte flags, comparison with the LH 755. International Journal Of Laboratory Hematology, 33(2), 138-145. doi: 10.1111/j.1751-553x.2010.01257.x

Seo, D., Ha, E., Cho, S., & Kim, S. (2016). Performance Evaluation of the DxH 800 Hematology Analyzer. Journal Of Laboratory Medicine And Quality Assurance, 38(4), 253-256. doi: 10.15263/jlmqa.2016.38.4.253